{"id":20,"date":"2015-01-14T18:27:44","date_gmt":"2015-01-14T18:27:44","guid":{"rendered":"http:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?page_id=20"},"modified":"2022-02-17T15:57:49","modified_gmt":"2022-02-17T15:57:49","slug":"research","status":"publish","type":"page","link":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?page_id=20","title":{"rendered":"Research"},"content":{"rendered":"<p><b><i>Current Research Interests:<\/i><\/b> Causal modeling of biomedical and clinical data; integration of multi-modal data using machine learning; clinical genomics; modeling transcriptional and post-transcriptional gene regulation; modeling of gene disease networks.<\/p>\n<p>Identifying direct (causal) associations between biomedical or clinical variables is key to designing Precision Medicine strategies.&nbsp;The Benos group develops machine learning methods to integrate heterogeneous data into a single probabilistic graphical framework. The resulting graphs can then be used to infer causal interactions, uncover disease mechanisms, select biomarkers or help stratify patient populations.<\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1108\" src=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-300x157.jpg\" alt=\"\" width=\"525\" height=\"275\" srcset=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-300x157.jpg 300w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-768x402.jpg 768w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-1024x536.jpg 1024w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-250x131.jpg 250w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1-150x79.jpg 150w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/Fig1.jpg 2000w\" sizes=\"auto, (max-width: 525px) 100vw, 525px\" \/>&nbsp;&nbsp;&nbsp;&nbsp;<\/a><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/Benos_pubs2017-19_wordcloud2.png\">&nbsp;<\/a><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-2073 \" src=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words-300x238.png\" alt=\"\" width=\"337\" height=\"267\" srcset=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words-300x238.png 300w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words-768x609.png 768w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words-189x150.png 189w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words-150x119.png 150w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/ABSTRACTS-for-BENOS-Lab-2018-2020Dec-cleaned_up_words.png 780w\" sizes=\"auto, (max-width: 337px) 100vw, 337px\" \/><\/a><\/p>\n<p><em>This WordCloud is based on titles and abstracts of papers published by members of the Benos&#8217; group during 2018-2020.<\/em><\/p>\n<p>Our lab is also part of the <em><strong><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?page_id=1799\" target=\"_blank\" rel=\"noopener\">Genomics and Systems Biology Core<\/a><\/strong>&nbsp;of the<\/em>&nbsp;<em><a href=\"https:\/\/www.livercenter.pitt.edu\" target=\"_blank\" rel=\"noopener\">Pittsburgh Liver Research Center<\/a>.<\/em><\/p>\n<div style=\"position: absolute;left: -53523px;\">\nPsychologists advise starting an acquaintance on the street with a girl with a question. The question makes you stop and think, it does not scare, but rather encourages communication. Do not ask banalities <a href=\"https:\/\/besthookup.io\/\">https:\/\/besthookup.io\/<\/a>, let your question surprise and interest, try different options. Subtle details, elements of clothing can tell a lot about a girl&#8217;s preferences and become an occasion for conversation. Does she have a phone case with her favorite character on it? That&#8217;s the topic of conversation when meeting.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Current Research Interests: Causal modeling of biomedical and clinical data; integration of multi-modal data using machine learning; clinical genomics; modeling transcriptional and post-transcriptional gene regulation; modeling of gene disease networks. Identifying direct (causal) associations between biomedical or clinical variables is key to designing Precision Medicine strategies.&nbsp;The Benos group develops machine &#8230;<\/p>\n<p> <a class=\"continue-reading-link\" href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?page_id=20\"><span>Continue reading<\/span><i class=\"crycon-right-dir\"><\/i><\/a> <\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/template-onecolumn.php","meta":{"footnotes":""},"class_list":["post-20","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/pages\/20","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20"}],"version-history":[{"count":28,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/pages\/20\/revisions"}],"predecessor-version":[{"id":2379,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/pages\/20\/revisions\/2379"}],"wp:attachment":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}