{"id":1067,"date":"2019-01-22T20:32:40","date_gmt":"2019-01-22T20:32:40","guid":{"rendered":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?p=1067"},"modified":"2019-03-01T10:18:19","modified_gmt":"2019-03-01T10:18:19","slug":"ajs-parp1-paper-is-accepted-in-scientific-reports","status":"publish","type":"post","link":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?p=1067","title":{"rendered":"AJ&#8217;s PARP1 paper is accepted in Scientific Reports"},"content":{"rendered":"<p><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1068 alignleft\" src=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-300x145.jpg\" alt=\"\" width=\"269\" height=\"130\" srcset=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-300x145.jpg 300w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-768x371.jpg 768w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-1024x494.jpg 1024w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-250x121.jpg 250w, https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2019\/01\/PARP1_Fig-150x72.jpg 150w\" sizes=\"auto, (max-width: 269px) 100vw, 269px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/AndrewSedgewick100X139.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-407 size-full\" src=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/wp-content\/uploads\/2015\/01\/AndrewSedgewick100X139.jpg\" alt=\"\" width=\"100\" height=\"140\" \/><\/a><br \/>\nCongratulations to AJ and our Pitt and MD Anderson colleagues for the latest paper that was accepted today in <em><strong>Scientific Reports<\/strong><\/em>! \u00a0This paper presents the discovery and validation of \u00a0a PARP1 SNP that is highly predictive of \u00a0chemotherapy resistance and suggests a new therapeutic strategy using chemotherapy in combination with PARP1 inhibitors.<\/p>\n<p>UPDATE 2019-03-01:\u00a0The paper is now available from the journal&#8217;s<em>\u00a0<\/em>web site (<a href=\"https:\/\/www.nature.com\/articles\/s41598-019-39542-2\" target=\"_blank\" rel=\"noopener\">here<\/a>). <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to AJ and our Pitt and MD Anderson colleagues for the latest paper that was accepted today in Scientific Reports! \u00a0This paper presents the discovery and validation of \u00a0a PARP1 SNP that is highly predictive of \u00a0chemotherapy resistance and suggests a new therapeutic strategy using chemotherapy in combination with &#8230;<\/p>\n<p> <a class=\"continue-reading-link\" href=\"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/?p=1067\"><span>Continue reading<\/span><i class=\"crycon-right-dir\"><\/i><\/a> <\/p>\n","protected":false},"author":3,"featured_media":1075,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1067","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/posts\/1067","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1067"}],"version-history":[{"count":7,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/posts\/1067\/revisions"}],"predecessor-version":[{"id":1304,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/posts\/1067\/revisions\/1304"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=\/wp\/v2\/media\/1075"}],"wp:attachment":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1067"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1067"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/benos\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1067"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}