Congratulations to Chaitanya and David for their first-author paper that was accepted at iScience!! In this work they develop a gravity-driven cell culture system that can be built from Arduino components and 3D-printed scaffolds. The system allows users to automate time-varying changes in the composition of cell culture media which can be used to probe signaling mechanisms in single cells. Their results with the cells expressing an NF-kB reporter suggest that the typical NF-kB response may be a byproduct of step-wise cytokine stimulation and not a defining characteristic of the signaling network. Their results also suggest there more signaling mechanisms to be discovered in regulation of NF-kB that can only be observed using dynamic cytokine stimulation. Check back in the next few weeks for a link to the accepted paper once it is published online. <\/p>\n","protected":false},"excerpt":{"rendered":"
Congratulations to Chaitanya and David for their first-author paper that was accepted at iScience!! In this work they develop a gravity-driven cell culture system that can be built from Arduino… <\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-502","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/posts\/502","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=502"}],"version-history":[{"count":4,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/posts\/502\/revisions"}],"predecessor-version":[{"id":507,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=\/wp\/v2\/posts\/502\/revisions\/507"}],"wp:attachment":[{"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=502"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=502"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csbweb.csb.pitt.edu\/Faculty\/lee\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=502"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}