Motivation ---------- * pyANCA proposes the use of anharmonicity in organizing the conformational landscapes of proteins and other biomolecules. * Traditional analysis tools for biomolecular simulations have focused on second-order statistics of atomic fluctuations. * Anharmonicity in time-dependent conformational fluctuations is noted to be a key feature of functional dynamics of biomolecules. While anharmonic events are rare, long timescale (μs-ms and beyond) simulations facilitate probing of such events. * This challenge was previously addressed by proposing anharmonicity as an organizing principle for conformational landscapes of proteins and other biomolecules. In particular, we have built quasi-anharmonic analysis (QAA) to resolve higher order spatial correlations :ref:`(see Ref. 1-7) `. In this work, we have extended this toolbox to resolve higher order temporal correlations. * A scalable Python package, anharmonic conformational analysis (pyANCA) is developed as an extensible software framework to characterize anharmonic events and enable a deeper analysis of their functional relevance. .. vim: tw=75