We reached an important milestone today. Kristina got a major part of her thesis work accepted for publication in the journal Bioinformatics. The paper describes a new method, single sample Network Perturbation Assessment (ssNPA), which learns a gene expression network (in the form of a directed graph) from a set of …
Takis gave a talk at the Computational Medicine Conference, where he presented both the algorithmic aspects and clinical applications of CausalMGM. The conference was organized by Drs Adrian Lee and Tim Lezon, with the support of the University of Pittsburgh Clinical and Translational Science Institute (Pitt CTSI). (Here Takis offers …
Congratulations to Dimitris for the acceptance of a paper he co-authored by the journal Critical Care Medicine. The paper, entitled “Host-Response Subphenotypes Offer Prognostic Enrichment in Patients With or at Risk for Acute Respiratory Distress Syndrome” is a collaboration with Dr. George Kitsios and other colleagues from the Division of Pulmonary …
Congratulations to Dimitris and Junke for the acceptance of the paper they co-authored: “A dynamic regulatory model of gene expression changes in differentially affected regions of the human IPF lung”. The paper will soon be published in the JCI Insight. This is an international collaboration to study the progress of idiopathic pulmonary …
The Benos Lab received a U01 grant to study the changes that occur in healthy lungs due to aging. We will collect and analyze single cell and bulk RNA-seq data and model the changes that occur in aging lungs and specific age-related pathways. Mouse experiments will be performed by our …